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List of selected publications from our research group exemplifying the projects we are conducting. Blom. A. M., Pertoft H. and Fries E. (1995) Inter-a-inhibitor is required for the formation of the hyaluronan-containing coat on fibroblasts and mesothelial cells. J. Biol. Chem., 270, 9698-9701. Blom A. M., Mörgelin M., Öyen M., Jarvet J. and Fries E. (1999) Structural characterization of inter-a-in

https://www.protein-chemistry.lu.se/top-publications/selected-publications-group - 2025-11-19

In blood, complement proteins are a major component and perhaps therefore most of these were identified already decades ago. However, only in recent years it has become apparent that complement not only plays a major role in innate defense against pathogens but also identifies foreign materials and removes waste (immune complexes and dying cells). The physiological relevance of complement is demon

https://www.protein-chemistry.lu.se/projects - 2025-11-19

We are studying an unexpected role of complement – in the physiology and metabolism of pancreatic beta-cells. Surprisingly, this is related to intracellular functions of complement and therefore changes the way we perceive this “blood” system and will likely inspire discovery of many other intracellular effects of complement. We study the role of intracellular complement factor C3 and membrane bou

https://www.protein-chemistry.lu.se/projects/insulin-and-immunity-when-complement-takes-control - 2025-11-19

As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens.  We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is

https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-11-19

  Misguided or excessive complement activation is involved in many common diseases such as rheumatoid arthritis, systemic lupus erythematosus, vasculitis and age-related macula degeneration. In collaboration with clinicians we are studying molecular mechanisms of complement involvement in these diseases. Joint inflammation in rheumatoid arthritis (RA), a common chronic inflammatory disease that ca

https://www.protein-chemistry.lu.se/projects/pathologic-complement-activation-diseases - 2025-11-19

Complement-dependent cytotoxicity is one of the mechanisms by which therapeutic monoclonal antibodies are toxic to cancer cells. Also, complement is currently undergoing re-appreciation of its role in the immune surveillance of tumors. The majority of human tumors are low immunogenic and complement may be involved in their recognition via direct “danger signal” elicited activation. This in turn at

https://www.protein-chemistry.lu.se/projects/complement-and-cancer - 2025-11-19

Complement has recently gained substantial worldwide attention, as it was discovered that several common diseases such as age-related macular degeneration (blindness in elderly) are related to deregulation of the balance between complement activation and inhibition. Full complement deficiencies lead to severe infectious and autoimmune diseases but are uncommon while it appears that we are just beg

https://www.protein-chemistry.lu.se/projects/inherited-deficiencies-complement-inhibitors - 2025-11-19

 You can reach us by mailor by calling 040-33 78 30 and 040-33 15 20Vaishnavi Dandavate, postdoctoral fellowE-mail: vaishnavi [dot] dandavate [at] med [dot] lu [dot] se (vaishnavi[dot]dandavate[at]med[dot]lu[dot]se)Daniel Chacón Arguedas, postdoctoral fellowE-mail: daniel [dot] chacon_arguedas [at] med [dot] lu [dot] seLucia Fernandez-Nevado, postdoctoral fellowE-mail: lucia [dot] fernandez_nevado

https://www.protein-chemistry.lu.se/members-our-research-group - 2025-11-19

Here you can find description of open positions and internships in our research group. MSc StudentsWe often can offer thesis projects for Masters students within the projects conducted in our group. Please, contact Anna Blom (Anna [dot] Blom [at] med [dot] lu [dot] se (Anna[dot]Blom[at]med[dot]lu[dot]se)) directly for more details.PhD StudentsWe are always interested in reviewing PhD students appl

https://www.protein-chemistry.lu.se/open-positions - 2025-11-19

Research funding supporting projects conducted in our research group: Swedish Research Council Cancerfonden Torsten Söderberg Foundation ALF Knut and Alice Wallenberg Foundation Novo nordisk fonden Erling-Persson Family Foundation Alfred Österlund Foundation  Grants for clinical research from Skåne University Hospital (including cancer) King Gustav Vth, 80-years Anniversary Foundation Diabetesfond

https://www.protein-chemistry.lu.se/research-funding - 2025-11-19

Medical Protein Chemistry Group. Who are we? Professor Anna Blom leads the Medical Protein Chemistry group Projects conducted in our research group Open positions Lund University Diabetes Centre Department of Translational Medicine

https://www.protein-chemistry.lu.se/protein-chemistry - 2025-11-19

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö. The group is focused on the complement system in health and disease. Our ambition is to make high quality basic science based on clinically relevant questions and yielding novel diagnostic approaches and clinical interventions. Our research is su

https://www.protein-chemistry.lu.se/anna-blom-research-group - 2025-11-19

LU student theses in connection with our research on N~Z nuclei near the proton dripline and isospin symmetry (breaking). PhD ThesesYuliia Hrabar, ongoingJnaneswari Gellanki, Comprehensive Gamma-ray Spectroscopy of  62Zn and Studies of Nilsson Parameters in the Mass A=60 Region, September 2013Robert Hoischen, Isotope-selective Spectroscopy: Fast Timing R&D and fp-Shell Mirror Isomers, March 2011Em

https://www.particle-nuclear.lu.se/experimental-particle-and-nuclear-physics/nuclear-structure/proton-dripline-studies/theses - 2025-11-19

Sampling publications on N~Z nuclei, isospin symmetry (breaking), and proton radioactivity. OverviewD. Rudolph et al., Exotic Decay Modes in Rotating Nuclei, Nucl. Phys. A 752, 241c (2005)J. Ekman et al., Mirror Symmetry in the Upper fp Shell, Mod. Phys. Lett. A 20, 2977 (2005)D. Rudolph, Studies of N~Z Nuclei Beyond 56Ni, in Achievements with the EUROBALL Spectrometer 1997-2003, 2004.D. Rudolph,

https://www.particle-nuclear.lu.se/experimental-particle-and-nuclear-physics/nuclear-structure/proton-dripline-studies/publications - 2025-11-19

The Bachelor's programme in physics is a three year programme resulting in a Bachelor of Science degree. The programme starts by giving you the physics and math tools you need to further your education, and as you specialize more and more the programme becomes flexible, giving you the opportunity to choose among the courses you are most interested in. There is a specialization for Theoretical Phys

https://www.particle-nuclear.lu.se/education/bachelors-programme - 2025-11-19

The experiments at ISOLDE cover questions over a variety of fields stretching from nuclear physics, nuclear astrophysics and laser physics to solid-state physics and medical physics. Our experiments are focused on nuclear astrophysics and nuclear physics at the higher end of the provided energy range. ISOLDE is CERN:s radioactive beam facility and provides radioactive ion beams using the Isotope S

https://www.particle-nuclear.lu.se/experimental-particle-and-nuclear-physics/nuclear-astrophysics-reactions/ISOLDE - 2025-11-19

The Reactions with Relativistic Radioactive Beams (R3B) experiment at FAIR focuses on kinematically complete measurements, primarily involving atomic nuclei far from stability, using relativistic beams. The Facility for Anti-proton and Ion Research (FAIR), which R3B is part of, is a new convention bound international accelerator facility where Sweden is a share holder and a founder member. The R3B

https://www.particle-nuclear.lu.se/experimental-particle-and-nuclear-physics/nuclear-astrophysics-reactions/r3b - 2025-11-19

After a Bachelor's degree in physics, you may want to continue to broaden and deepen your knowledge and apply for a two-year master's degree in physics. There are two specialisations on the master programme in physics centered around research at our division, which are offered by the Department of Physics: the master programme with specialisation in Theoretical physics, and the master programme wi

https://www.particle-nuclear.lu.se/education/masters-programme - 2025-11-19

We are working towards establishing a research program in fundamental physics at ESS together with colleagues. Our interest is primarily in neutrino physics at low energies, but we are also involved in exploring the possibilities for a long-baseline neutrino oscillation experiment. When the ESS linear accelerator reaches its nominal power it will be the primary high-intensity proton machine in the

https://www.particle-nuclear.lu.se/experimental-particle-and-nuclear-physics/nuclear-astrophysics-reactions/ESS - 2025-11-19

The Division of Particle and Nuclear Physics offers a postgraduate education - a PhD education - equivalent to four years of full-time studies (240 credits or ECTS). The programme consists of both courses and thesis work. The research thesis can be written in the wide range of subjects, represented in the different research areas represented in the Division. After completion, the student receives

https://www.particle-nuclear.lu.se/education/post-graduate-programme - 2025-11-19